George Clinical’s Scientific Leaders transform site performance.
Professor Vlado Perkovic
Vlado Perkovic is Executive Director of The George Institute, Australia and George Clinical, and a Professor of Medicine at The University of Sydney. He is a Staff Specialist in Nephrology at the Royal North Shore Hospital and has led the development of George Clinical, the global clinical trials arm of The George Institute.
His research focus is in clinical trials and epidemiology, in particular in understanding both the cardiovascular risk associated with kidney disease and the impact of interventions that might mitigate this risk. He has been involved in developing Australian and global guidelines in kidney disease, cardiovascular risk assessment and blood pressure management. Vlado holds a Doctor of Philosophy from the University of Melbourne and completed his undergraduate training at The Royal Melbourne Hospital.
He is a member of the National Health and Medical Research Council Academy; is Chair of the Scientific Committee of the Australasian Kidney Trials Network; and is a Fellow of the Royal Australasian College of Physicians and of the American Society of Nephrology.
Professor Bruce Neal
Bruce Neal is a Senior Director at The George Institute for Global Health, Professor of Medicine at the University of Sydney and Chair of the Australian Division of World Action on Salt and Health.
Dr Neal is a UK-trained physician who has 20 years research experience in the clinical, epidemiological, and public health fields with a focus on heart disease, stroke and diabetes. Bruce has a longstanding interest in the environmental determinants of high blood pressure and the potential for changes in the food supply to deliver health gains. His work has been characterised by its focus on collaboration, quantitation, translation and impact.
Dr Neal holds professorial appointments at the University of Sydney, Imperial College London and Flinders University in South Australia and chairs the Australian Division of World Action on Salt and Health. He has published some 300 scientific papers and in 2016 was identified by Thomson Reuters as one of ‘The World’s Most Influential Scientific Minds’, an acknowledgement provided to just 3000 researchers across all disciplines, worldwide. He has particular expertise in salt reduction but also a broader knowledge of food policy issues related to sugars, fats, portion size and food labelling.
Associate Professor Meg Jardine
A/Prof Meg Jardine is a clinician researcher developing a program of research exploring the cardiovascular and other complications of chronic kidney disease and diabetes. Dr Jardine has worked as a Nephrologist in both the public and private sectors, where she directly manages chronic kidney disease and diabetes and their consequences for patients.
She is currently Deputy Director of the Renal & Metabolic Division at the George Institute for Global Health, and Associate Professor at Sydney Medical School and holds an NHMRC Career Development Fellowship. She has presented her work in Late Breaking and prize sessions of the World Congress of Nephrology and the Australasian Nephrology conference and has published in high impact journals. Dr Jardine is collaborating on the development and delivery of other national and international trials investigating methods to mitigate the excess burden of cardiovascular disease and is Chair of the Australasian Kidney Trials Network Haemodialysis Working Group.
Professor Clara Chow
Clara Chow is Director of the cardiovascular division of The George Institute, Program Director Community Based Cardiac Services, Westmead Hospital and Associate Professor with the Faculty of Medicine University of Sydney.
She has a PhD in Medicine from the University of Sydney and completed a postdoc in cardiovascular epidemiology and clinical trials at McMaster University, Canada. Clara holds a Career Development Fellowship of the NHMRC co-funded by the National Heart Foundation. Her research focus is clinical and community approaches to cardiovascular disease prevention.
Professor Christine Jenkins
Christine Jenkins is Head of Respiratory Trials at The George institute for Global Health, Senior Staff Specialist in Thoracic Medicine at Concord Hospital, Sydney, and Clinical Professor and Head of Respiratory Discipline at the University of Sydney.
Christine has been Principal Investigator and has led many investigator-initiated and competitively funded clinical trials in airways disease. She has had major roles in advocacy and leadership for lung health in Australia, chairing the National Asthma Campaign, the Federal Government’s National Asthma Advisory Group and many local and international guidelines and implementation initiatives to enhance resources, skills, capacity and clinical outcomes in airways disease. She was president of the Thoracic Society of Australia and New Zealand from 2007 – 2009.
Christine is an active clinician, and teaches and supervises medical students, advanced trainees and post graduate students. She heads the Respiratory Discipline in the Faculty of Medicine at the University of Sydney
Christine’s area of research interest is the clinical management of airways disease and patient reported outcomes in response to therapeutic interventions, and she is currently implementing trials in asthma and COPD management and pulmonary rehabilitation in Australia and Asia.
Christine has written two books on asthma, one for medical students and one for patients, their families and carers. In 2002 she was made a Member in the Order of Australia for recognition of service to respiratory medicine as a physician, administrator and educator, especially in the field of asthma education. She is on the Board of the Lung Foundation Australia, and is a member of the Thoracic Society of Australia and New Zealand, the American Thoracic Society, European Respirator Society and the Asia-Pacific Society of Respirology.
Professor Emeritus Norbert Berend
Norbert Berend is Head of Respiratory Research at the George Institute for Global Health and a member of the physiology group at the Woolcock Institute of Medical Research of which he was the Director from 2000 to 2012. He holds the academic title of Professor Emeritus at the University of Sydney and is a Visiting or Honorary Professor at three Chinese Universities.
He is a past President of the Thoracic Society of Australia and New Zealand and the Asian Pacific Society of Respirology. He has also held positions with the American Thoracic Society and European Respiratory Society. Norbert’s research interests include the pathophysiology of asthma and COPD and clinical intervention studies to improve the outcome of airways disease.
Norbert is a recipient of the TSANZ Medal, the APSR Medal and has received an Award of Merit from the European Respiratory Society. In 2003 Norbert was made a Member of the Order of Australia for services to respiratory medicine.
Professor Craig Anderson
Craig Anderson is Professor of Stroke Medicine and Clinical Neuroscience in the Sydney Medical School at the University of Sydney and the Institute of Neurosciences of Royal Prince Alfred Hospital. Having led several major international stroke studies, Craig is widely acknowledged as a leader in his field.
He was recently awarded the Royal Prince Alfred Research Medal for Excellence in Research. Craig is a member of several specialist societies, an Editor for the Cochrane Stroke Group, and a former President of the Stroke Society of Australasia. He has published widely on the clinical and epidemiological aspects of stroke, cardiovascular disease and aged care. He is on the Steering Committee for several large-scale research projects.
Professor Simon Finfer
Simon Finfer is a Professorial Fellow in the Critical Care and Trauma Division at The George Institute. He is a practicing critical care physician with an appointment as a Senior Staff Specialist at Royal North Shore Hospital and Director of Intensive Care at the Sydney Adventist Hospital, the largest private hospital in New South Wales.
Simon is an Adjunct Professor at the University of Sydney Medical School, a past-Chair of the Australian and New Zealand Intensive Care Society (ANZICS) Clinical Trials Group. He is a council member of the International Sepsis Forum and the Global Sepsis Alliance, and a member of the World Sepsis Day Steering Committee.
His postgraduate qualifications include Fellowships of the Royal Colleges of Physicians, the Royal College of Anaesthetists and the College of Intensive Care Medicine. He was elected to the ANZICS Honour Roll in 2011 and in 2012 he was awarded an honorary doctorate (Doctor of Medicine) by The Friedrich-Schiller University in Germany, an honour awarded once every 10 years.
Simon’s major research interest is the design and conduct of large scale randomised controlled trials in critical care. Simon is active in forging major international research collaborations that have conducted large scale clinical trials and epidemiological research to improve the treatment of critically ill and injured patients.
Simon is an Editor of The Oxford Textbook of Critical Care (2nd Ed.), the Critical Care Section Editor for The Oxford Textbook of Medicine (6th Ed.), and is currently a guest editor for The New England Journal of Medicine.
Professor John Myburgh AO
Professor John A Myburgh AO, is Director of the Division of Critical Care and Trauma at the George Institute for Global Health, Professor of Critical Care at the Faculty of Medicine, University of New South Wales and senior intensive care physician at the St George Hospital, Sydney. He holds honorary professorial appointments at University of Sydney and Monash University School of Public Health.
He has an extensive research track record over 25 years and is regarded as a national and international expert in catecholamine neurophysiology and pharmacology, trials of clinical management of traumatic brain injury, fluid resuscitation and in the development and co-ordination of multi-centred clinical studies in Intensive Care Medicine.
His list of publications and success in recurrent grant funding is in the top 1% of Intensive Care physicians in Australia and within the top 5% internationally. These include over 160 refereed research publication and 45 book chapters and monographs. He has received over $40M in grant funding including a NHMRC Practitioner Fellowship in 2012 and delivered over 300 presentations at national and international scientific meetings since 1994.
He is a Foundation Member and Immediate Past-Chairman of the Australian and New Zealand Intensive Care Society Clinical Trials Group. In addition to his research profile, he has a long-established national profile in education in Intensive Care Medicine and was instrumental in establishing the College of Intensive Care Medicine, serving as the first elected President from 2010-2012.
In June 2014, John was recognised as an Officer (AO) in the General Division of the Order of Australia for distinguished service to medicine as an intensive and critical care practitioner, educator and researcher, and as an international innovator in patient management.
Professor Vivekanand Jha
Professor Vivekanand Jha is the Executive Director, The George Institute for Global Health, India, and James Martin Fellow at The George Institute for Global Health at the University of Oxford.
Prior to joining The George Institute, he was Professor of Nephrology and Head, Department of Translational Regenerative Medicine and Officer-In-Charge, Medical Education and Research Cell at the Postgraduate Institute of Medical Education and Research in Chandigarh, India. Vivek serves on the international advisory boards of several organisations, including membership of the WHO Expert Advisory Panel on Human Cell, Tissue and Organ Transplantation, and the executive committee of the International Society of Nephrology.
He is a councillor of the International Society of Nephrology, a member of the education committees for the International Transplantation Society and International Society of Peritoneal Dialysis. He is a physician with a specialisation in the area of kidney diseases and he focuses on emerging public health threats globally and in India. He is particularly interested in using multi-disciplinary approaches and innovation to address the major challenge posed to humanity by non-communicable diseases.
Professor Kazem Rahimi
Kazem Rahimi is the James Martin Senior Fellow in Essential Healthcare at the University of Oxford and Honorary Consultant Cardiologist at the John Radcliffe Hospital, Oxford. As the Deputy Director of The George Institute UK he leads the Essential Healthcare Programme, which aims to find practical and affordable solutions for the global health priorities of the world’s largest emerging economies, as well as the priorities of vulnerable or disadvantaged populations in established economies.
He graduated in medicine from the University of Leipzig in Germany with postgraduate training in cardiology and health services research in Leipzig, London and Oxford. Prior to joining the George Institute, in 2010, he was a Research Fellow at Oxford’s Clinical Trial Service and Epidemiological Studies Unit. His research interests include service delivery innovation in chronic disease prevention and management, large-scale complex intervention studies, and data-driven electronic decision support systems.
Professor Anthony Rodgers
Anthony Rodgers is a Professor of Global Health at The George Institute. After graduating in medicine in the United Kingdom he trained in epidemiology and public health in New Zealand. He was the Principal Author of the 2002 World Health Report, the main annual publication for WHO.
Since 2003 he has led a public-private partnership developing an affordable four-in-one cardiovascular combination pill (‘polypill’), with a clinical trial program in economically developed and developing countries. His current work aims to foster similar developments designed to be ‘fit for purpose’ in low income settings.
Associate Professor Martin Gallagher
Martin is an Associate Professor of Medicine at Concord Hospital Clinical School (part of the Sydney Medical School), Senior Director of the Renal and Metabolic Division in the George Institute and Head of the Renal Dept at Concord Repatriation and General Hospital. He is also Chair of the KHA-CARI Guidelines Steering Committee, the group that leads renal guideline development in Australia and New Zealand.
Martin’s research interests include large scale clinical trials to explore ways to improve the outcomes of patients with kidney disease (especially in the setting of acute kidney injury), extending the follow up of such clinical trials to understand the long term effects of treatments, measurement of health systems and the means of applying research evidence into practice.
Dr Muh Geot Wong
Dr Wong is Renal Physician at the Royal North Shore hospital, Sydney, Australia. He is also a senior research fellow at the George Institute of Global Health and a senior clinical lecturer at the University of Sydney. His PhD entitled “Novel therapeutic options in models of nephropathy” was awarded in 2011.
His main area of research is in understanding the pathomechanisms of kidney tubulointerstitial fibrosis and biomarkers in predicting progression of chronic kidney disease particularly in diabetic kidney disease.
Dr Wong has worked on kidney injury molecule-1, transforming growth factor-β1, bone morphogenetic protein-7, Farnesoid X receptor and novel anti-fibrotic and anti-inflammatory agents in extracellular matrix deposition in human proximal tubular cells and in vivo model of fibrosis.
His is also passionate in translation medicine and is involved in the post hoc analyses of the IDEAL study and currently involved in multicentre international trials at the George Institute including TESTING and SONAR study.
Professor John Chalmers AC
John Chalmers AC FAA has an outstanding record in hypertension research, both fundamental and clinical. His ground-breaking research on the role of the brain in the development of hypertension led to his election to Fellowship of the Australian Academy of Science and helped establish Flinders University as a leading international centre in hypertension and neuroscience research.
His studies on the treatment of high blood pressure for the prevention of heart attack and stroke has changed the way patients are treated throughout the world. His work has been recognised through many awards including the Wellcome Medal, the RT Hall Prize of the Cardiac Society of Australia and New Zealand, and the Volhard Medal of the International Society of Hypertension.
Professor Chalmers’ contribution to medical science has been acknowledged through the award of many Honorary Doctoral degrees and extensive appointments on national and international boards and advisory committees. He was appointed a Companion in the Order of Australia (AC) in 1991 and awarded the Centenary Medal in 2003 in recognition of services to medical science and to Australian society.
John Chalmers remains an active researcher at The George Institute Australia, where he holds the title of Senior Director. He is a principal investigator on many research grants and steering committees for major studies, mentors young clinical researchers from around the world, and continues to publish and lecture prolifically.
Associate Professor Laurent Billot
Laurent is Director of the Statistics Division at the George Institute and Principal Research Fellow at The University of Sydney. He is an accredited statistician by the Statistical Society of Australia. Laurent has a master degree in Statistics and Computer Science from the University of South-Brittany (France) and an advanced degree in Public Health and Biostatistics from the University of Paris V.
Prior to joining the George Institute in 2006, Laurent worked at the School of Public Health of the University of Nancy I (France) and at Statistics Collaborative Inc. (USA), a contract research organisation specialised in the design and analysis of biomedical studies. Over the last fifteen years, Laurent has been responsible for the design, analysis and reporting of numerous medical studies ranging from health surveys and epidemiological studies to multinational Phase III/IV trials in oncology, critical care and cardiovascular disease.
Professor Stephen Jan
Stephen Jan is a Senior Health Economist, Professor in the Sydney Medical School and an Associate at the Menzies Centre for Health Policy. Stephen’s areas of research interest are economic evaluation alongside clinical and public health studies, Aboriginal and Torres Strait Islander health, health systems research, the analysis of the household economic impact of chronic illness, institutionalist economics and health policy.
As an economist working mainly with public health researchers, he is involved in projects across numerous disease areas and in collaborations with partners within the Institute and outside. He is the lead Chief Investigator on an NHMRC Capacity Building Grant in Health Services Research which funds traineeships for a number of health economics researchers at the George Institute and the University Sydney.
Professor Mark Woodward
Working in the Professorial Advisory Unit of The George Institute, Mark is also a Professor of Biostatistics at the University of Sydney, Professor of Statistics and Epidemiology at the University of Oxford and Adjunct Professor of Epidemiology at Johns Hopkins University.
He is the author of 400+ peer-reviewed publications and two text-books on statistical methods in medical research, one of which had its third edition published in January 2014. In the five year period from January 2009 to December 2013 he published 161 (>40% of his total) peer-reviewed publications, including seven in The Lancet, two in NEJM and one in JAMA. Three of his papers have over a thousand citations.
Mark has led four major international studies and directed the analytical research on three landmark collaborative studies, worldwide. His work on cardiovascular risk scores formed the basis of national guidelines in Scotland, and his recent work on kidney disease was used to produce new staging criteria for this disease. His total career grant awards are over $93 million from 39 successful applications.
He also has extensive experience in student teaching, postgraduate supervision and mentoring including 14 PhD and 19 MSc students successfully completed. He has given training workshops in Korea and Thailand, and has taught at least 25 other research training courses.
Mark served on the governing council of the Institute of Statisticians and the Royal Statistical Society (RSS) and is currently a fellow of the RSS, the European Society of Cardiology, the New York Academy of Medicine and the Royal Society of Medicine.
He has wide experience of development aid work in Africa and Asia, having undertaken 25 missions for aid agencies, such as the WHO. He has also assessed grants for six national medical research councils (including NHMRC) and served on the editorial boards of seven international journals.