A randomised controlled double-blind study comparing the effects of saline versus albumin on mortality in 6,997 patients, with up to 30 days of follow-up.
Saline vs Albumin
Read more about the SAFE trial on The George Institute website
This trial was completed under budget and ahead of schedule, with results published in The New England Journal of Medicine.
Impact
6,997 patients, two countries, 16 centres