Case Studies

George Clinical’s Renal Experience Proves Valuable in Largest Corticosteroid Study in IgA Nephropathy

Download The Complete Case Study   The determination of strong scientific leaders keeps trial on track to provide valuable data. SITUATION Despite optimal current care, up to 30% of people suffering from IgA nephropathy (IgAN) will develop kidney failure requiring dialysis or kidney transplantation. The largest corticosteroid trial in IgAN completed to date provided valuable […]

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May 8th, 2024

George Clinical Exceeds Recruitment and Retention Goals in Important Global IgA Nephropathy Study

Download The Complete Case Study   George Clinical Exceeds Recruitment and Retention Goals in Important Global IgA Nephropathy Study At the peak of the COVID pandemic, recruitment was met, and patient visits continued safely. SITUATION IgA Nephropathy (IgAN) is a disease with a relative lack of progress in innovation and a population largely absent from […]

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April 8th, 2024

George Clinical Helps Biotech Deliver Cell and Gene Therapy Study with Best-in-Class Data

Download The Complete Case Study   Early risk identification and comprehensive quality management plan ensured best possible outcome.   SITUATION Neoantigen vaccines have appeared only recently as emergent immunotherapy and show great promise. Biopharmaceutical companies developing these drugs often have few resources and no experience in conducting the unique and complex clinical trials associated with […]

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March 6th, 2024

George Clinical Assists Small Biopharmaceutical Company in Important USA Osteosarcoma Study

Download The Complete Case Study   Collaborative teamwork results in success for this study involving rare indication in a pediatric / young adult population. According to research, emerging biopharma companies (EBPs) are responsible for two-thirds of all molecules in the R&D pipeline, and many of the drugs in development are promising candidates for rare diseases. […]

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December 1st, 2023

George Clinical Successfully Delivers Complex Phase I Oncology Trial Within Agreed Timeline Despite Competitive Recruitment Landscape

Download The Complete Case Study   Early phase oncology expertise and established local relationships make George Clinical the CRO of choice for Chinese biotech.   Situation Our organization’s nimble, flexible approach to early phase oncology trials was a large benefit to an innovative, global Chinese biotech for a phase I, multicenter, open-label, dose-escalation, oncology clinical […]

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October 3rd, 2023

George Clinical Rescues Phase III Oncology Study From Trial Closure and Initiates Global Expansion

Download The Complete Case Study   First patient screening in seven months avoided lapse in Chinese regulatory approval.   SITUATION A pharmaceutical sponsor with a US Phase III metastatic pancreatic cancer study had previously applied for Chinese regulatory approval (NMPA). However, due to the impact of COVID-19 and other administrative reasons, no site identification or […]

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May 18th, 2023

George Clinical Team Guides Unique Multiple Sclerosis Trial Through Difficult Circumstances

Download The Complete Case Study   Challenges included specialized equipment, interaction with multiple departments and stringent COVID restrictions.   SITUATION George Clinical was chosen by a biopharmaceutical company focused on neurodegenerative disease to conduct a Phase II, randomized, double-blind, parallel group, placebo controlled clinical trial for the treatment of visual pathway deficits in chronic optic […]

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December 8th, 2022

George Clinical Renal Scientific Leadership Team Keeps Recruitment on Target in Difficult CKD Study

Download The Complete Case Study   Despite operational delays, COVID interruptions and Ukraine war outbreak, targets were met.   SITUATION George Clinical was chosen by a large pharmaceutical company to provide scientific leadership services across all participating countries in an ongoing Phase IIb, randomized, double-blind, placebo-controlled, multicenter study to assess the reduction of albumin in […]

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October 28th, 2022

Established Relationships Allow George Clinical to Meet Tight Timelines and Recruitment Challenges in Critical Early Phase Oncology Study

Download The Complete Case Study   Local knowledge combined with Australia’s favorable conditions keep trial on track and on time. Early phase clinical trials are the first-line research studies in drug development and assess therapies for safety, dosage levels and side effects. These studies form the basis for all further research on therapy, so they […]

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July 12th, 2022

George Clinical Brings Robust Retention Strategy and Tactics to Global Rare Renal Disease Studies

Download The Complete Case Study   We work to keep every patient engaged to the end from risk retention and personal contact with clinical research associates (CRAs) to patient-facing animation in 20 languages. Clinical trials for rare diseases pose specific challenges due to their elusive nature and low patient populations. Research is critical for these […]

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June 21st, 2022

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