Lowering blood pressure to decrease risk of cardiovascular events

Globally, there are millions of people that could benefit from an intensive lowering of blood pressure (BP). An individual with lower BP decreases their chances of suffering from any cardiovascular events such as: stroke, heart disease or heart attacks. A new study shows that lowering blood pressure to less than 140 mm Hg, the current […]

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Intensive blood pressure lowering reduces heart attacks

One quarter of the world’s adult population suffers from hypertension, and although it has no obvious symptoms, it can lead to heart attacks, stroke, kidney failure and blindness. Despite this, there has been great uncertainty as to how intensively blood pressure should be lowered to obtain maximal benefit and minimize risks. Researchers from Australia, China, […]

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Benefits of DPPIV-inhibitors still uncertain

The recent SAVOR-TIMI 53 (saxagliptin) and EXAMINE (alogliptin) trials recently reported the effects of the DPPIV inhibitor class of glucose lowering agents in people with diabetes. As required by the US FDA, both drugs were found not to increase cardiovascular risk, allowing the agents to be registered for use in that country. Good news, it would […]

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Lessons from the EVOLVE study

Cinacalcet is a drug that lowers levels of parathyroid hormone, a factor that is increased in almost all people with kidney failure and has been linked to an increased risk of fracture, cardiovascular events and death. It has been hoped that by reducing parathyroid hormone with cinacalcet, the risk of these clinical events will also […]

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