CMO Corner

ASCO 2022 Presentations Show Promise for Paradigm Shifts in Cancer Diagnosis and Treatments

That leaves 80% of mBC patients with fewer treatment options. However, research has shown that 55%-60% of these actually express low levels of HER2, and this is the category that Destiny-04 targeted, demonstrating that the legacy cutoff point to determine HER2 positivity can now be extended. These results establish HER2-low metastatic breast cancer as a […]

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August 11th, 2022

2022 ASCO Addresses Disparities in Cancer Care and Research

COVID era innovations will help shape the future for more equitable representation. Oncology professionals from around the world attended the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting in June, one of the largest oncology research conferences of the year. Researchers presented breakthrough clinical trial data including new treatment options, symptom management and research […]

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June 21st, 2022

Negative Effect of Pandemic on Cancer Survivorship Will Take Years to Calculate

Millions of screenings and treatments have been missed resulting in a rise in metastatic cancers. Cancer survivorship has made great strides, with death rates declining 31% since 1991 and oncology clinical trials dominating therapeutic focus. But cancer patients require uninterrupted care, and the full impact on survivorship of disruptions in care caused by the pandemic […]

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April 8th, 2022

COVID-19 Has Reshaped the Future Path of Clinical Trial Operations

COVID-19 propels clinical trial innovations from prolonged conjecture to a paradigm shift. Between March and November of 2020, COVID-19 negatively affected more than 1,200 clinical trials worldwide. Some were shut down completely while others were affected by lockdowns, patients becoming reluctant to continue with a trial or a host of other pandemic-related interruptions. As in […]

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February 22nd, 2022

More Effective Therapeutics for Rising Cardio Renal Metabolic Diseases Highlight Need for Multidisciplinary Approach to Health

Written by Maria Ali in collaboration with Suzanna Phelps-Fredette Medical history began with a holistic approach Medical philosophy and practice dates back to the Indian Ayurvedic system of medicine and ancient Greek, Roman and Islamic physicians. Both took a holistic approach that considered the physical, mental and emotional health of a person as well as […]

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October 28th, 2021

Conducting Early Phase Trials in the APAC Region

Excellent resources, proven experience and financial incentives make APAC a smart choice for First-in-Human and early phase clinical trials.   Clinical trials are moving east Challenges to conducting trials in the West, especially recruitment difficulties, have made the APAC region a preferred destination for clinical trials. APAC offers a high availability of patients, worldwide accepted […]

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July 30th, 2021

Bridging The Gap Between Research And Clinical Care

When clinical trials become a normal part of care options for patients with unmet needs, both researchers and patients will reap exponential rewards. “Where are the patients?” Clinical trials hinge on recruitment, and enrollment issues are a perpetual challenge. Research estimates that, on average, around 20-25% of trials across all phases and therapeutic areas are […]

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April 16th, 2021

Conducting Major COVID-19 Trial at Height of Worldwide Lockdown: Extraordinary Achievements Under Unprecedented Conditions

George Clinical teams draw on proven working models, established global relationships and unflinching dedication to implement clinical trial in a matter of weeks. In the dark times of global COVID-19 lockdowns, scientists and healthcare workers pressed forward in their mission of caring for and protecting the sick, particularly those who were contracting COVID-19. The global […]

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January 21st, 2021

Clinical Trial Innovations: Patient-Centric Value Added Into the Process Will Enhance the Scope and Influence of Clinical Trials for the Healthcare Community

The following article is written by George Clinical’s CMO, Maria Ali.   When outcomes are all that drive us we miss out on many important opportunities.   There has been a clear paradigm shift over the last few decades with regard to patients’ role in their medical care and treatment options. The old system whereby a […]

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July 21st, 2020

CMO Corner Interview with Vivekanand Jha

George Clinical CMO, Maria Ali, talks with ISN President Vivekanand Jha about renal disease in the developing world. Professor Jha is also the Executive Director at The George Institute for Global Health India, member of the Scientific Leadership Committee at George Clinical and a James Martin Fellow at The George Institute for Global Health, University […]

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February 28th, 2020

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